INT252907

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0

cytoplasm (PTTG1, PTTG2) chromosome organization (PTTG1, PTTG2) nucleus (PTTG1, PTTG2) chromosome segregation (PTTG1) cytosol (PTTG1) mitosis (PTTG1)

PTTG1 (Homo sapiens) PTTG2 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 9 5.00 Central nervous system 1 5.00 Kinase C 1 5.00 Inflammation 1 5.00 Pain 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Liver Cancer 3 84.24 Ovarian Cancer 16 50.00 Pituitary Cancer 13 17.28 Cancer 87 10.20 Targeted Disruption 27 5.00 Apoptosis 18 5.00 Metastasis 12 5.00 Aneuploidy 8 5.00 Thyroid Neoplasm 6 5.00 Hyperplasia 5 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The Neighbor phylogenetic tree analyses of human PTTG homologues revealed that PTTG2 and PTTG3 are more similar and formed a cluster leaving PTTG1 separate (Fig. 2).

PTTG1 Binding (formed) of PTTG2

1) Confidence 0.07 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.