INT252991

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.54
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TAF9) nucleolus (TAF9) nucleus (TAF9)
DNA binding (TAF9) kinase activity (TAF9)
Anatomy Link Frequency
muscles 1
A549 1
TAF9 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 6 95.60 Very High Very High Very High
Inflammation 13 57.36 Quite High
corticosteroid 48 25.00 Low Low
Action potential 22 5.00 Very Low Very Low Very Low
cytokine 14 5.00 Very Low Very Low Very Low
metalloproteinase 9 5.00 Very Low Very Low Very Low
sodium channel 6 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Muscle Disease 182 100.00 Very High Very High Very High
Neuropathy 160 100.00 Very High Very High Very High
Critical Illness 42 99.16 Very High Very High Very High
Sepsis 26 96.96 Very High Very High Very High
Systemic Inflammatory Response Syndrome 10 96.32 Very High Very High Very High
Multiple Organ Failure 18 92.72 High High
Lung Cancer 4 92.52 High High
Apoptosis 22 91.56 High High
Cancer 87 75.00 Quite High
Aneuploidy 8 68.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
They observed no change in the levels of expression of p53 and p21WAF1/CIP1 in PTTG1 overexpressed HeLa cells, whereas the p21WAF1/CIP1 was overexpressed by PTTG1 in A549 cells.
Neg (no) Regulation (change) of CIP1 in A549
1) Confidence 0.44 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.99 Pain Relevance 0
CIP/CIM prolongs weaning from mechanical ventilation and physical rehabilitation since both limb and respiratory muscles can be affected.
Regulation (affected) of CIP in muscles associated with neuropathy and muscle disease
2) Confidence 0.33 Published 2008 Journal Crit Care Section Abstract Doc Link PMC2646339 Disease Relevance 1.70 Pain Relevance 0.05
Multivariate analysis attributed the beneficial effect on CIP/CIM to glycemic control [43], whereas the beneficial effect on prolonged mechanical ventilation was due to the insulin dose and was not completely explained by the benefit on CIP/CIM [44].
Regulation (effect) of CIP associated with neuropathy and muscle disease
3) Confidence 0.23 Published 2008 Journal Crit Care Section Body Doc Link PMC2646339 Disease Relevance 0.85 Pain Relevance 0.03

General Comments

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