INT253021

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PTTG1, Fgf2) nucleus (PTTG1, Fgf2) cell differentiation (Fgf2)
chromosome segregation (PTTG1) embryo development (Fgf2) cytosol (PTTG1)
Anatomy Link Frequency
thyroid 2
PTTG1 (Homo sapiens)
Fgf2 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 36.32 Quite Low
metalloproteinase 9 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 87 100.00 Very High Very High Very High
Metastasis 12 68.00 Quite High
Esophageal Cancer 2 52.48 Quite High
Ovarian Cancer 16 50.00 Quite Low
Pain 1 36.32 Quite Low
Thyroid Neoplasm 6 24.92 Low Low
Targeted Disruption 27 5.00 Very Low Very Low Very Low
Apoptosis 18 5.00 Very Low Very Low Very Low
Pituitary Cancer 13 5.00 Very Low Very Low Very Low
Aneuploidy 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From these observations, these investigators concluded that PTTG1 may promote tumor angiogenesis by regulating the expression of angiogenic genes such as VEGF, bFGF, ID3, and TSP-1, suggesting that PTTG1 may be a key gene in thyroid tumorigenesis.
PTTG1 Regulation (regulating) of Gene_expression (expression) of bFGF in thyroid associated with cancer
1) Confidence 0.04 Published 2008 Journal J Ovarian Res Section Body Doc Link PMC2584053 Disease Relevance 0.35 Pain Relevance 0

General Comments

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