INT253070

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Prok2) extracellular region (Prok2) nucleus (Ik)
Anatomy Link Frequency
immune cells 2
T cell 2
Prok2 (Mus musculus)
Ik (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 84 100.00 Very High Very High Very High
Inflammatory response 2 92.84 High High
Inflammation 24 91.44 High High
antagonist 2 87.24 High High
IPN 2 57.80 Quite High
agonist 6 50.00 Quite Low
addiction 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 92.44 High High
Immune System Diseases 2 79.96 Quite High
Cancer 2 60.72 Quite High
Inflammatory Pain 2 57.80 Quite High
Immunization 20 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As PROKRs are present on all cell types present in the spleen, it is likely that Bv8 regulates cytokine production binding to multiple immune cells.
Bv8 Spec (likely) Regulation (regulates) of Gene_expression (production) of cytokine in immune cells associated with cytokine
1) Confidence 0.01 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2584092 Disease Relevance 0 Pain Relevance 0.09
We show that Bv8 plays a specialised role in modulating T cell cytokine production as it significantly reduces IL-4 and IL-10.
Bv8 Regulation (modulating) of Gene_expression (production) of cytokine in T cell associated with cytokine
2) Confidence 0.01 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2584092 Disease Relevance 0.60 Pain Relevance 0.47

General Comments

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