INT253073

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand2) extracellular space (Il4) extracellular region (Il4)
nucleus (Hand2) DNA binding (Hand2) protein complex (Hand2)
Anatomy Link Frequency
Th2 cells 1
Il4 (Mus musculus)
Hand2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 12 93.28 High High
cytokine 42 92.24 High High
agonist 3 50.00 Quite Low
Spinal cord 1 27.84 Quite Low
addiction 1 5.00 Very Low Very Low Very Low
IPN 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 1 100.00 Very High Very High Very High
Injury 1 99.56 Very High Very High Very High
INFLAMMATION 13 93.28 High High
Hematological Disease 1 69.28 Quite High
Hyperalgesia 1 60.48 Quite High
Targeted Disruption 1 22.96 Low Low
Immunization 10 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Immune System Diseases 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-12 is the critical factor driving the development of Th1 cells, which are associated with cell immune responses and tissue injury [20-23], whereas the Th2 cells responsible for humoral responses and allergies are stimulated by IL-4, which is produced by Th2 lymphocytes themselves [21,22,24].
IL-4 Positive_regulation (stimulated) of Th2 in Th2 cells associated with hypersensitivity and injury
1) Confidence 0.10 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2584092 Disease Relevance 0.59 Pain Relevance 0.31

General Comments

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