INT253075

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.24
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Prok2, Il10) cell proliferation (Prok2) extracellular space (Il10)
intracellular (Il10)
Anatomy Link Frequency
T lymphocytes 2
Prok2 (Mus musculus)
Il10 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 99.98 Very High Very High Very High
Inflammation 24 92.56 High High
cytokine 84 86.00 High High
addiction 2 5.00 Very Low Very Low Very Low
IPN 2 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 26 92.56 High High
Immunization 20 72.20 Quite High
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Hematological Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Immune System Diseases 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Inflammatory Pain 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1

Background

Bv8 Negative_regulation (decreases) of Gene_expression (production) of IL-10 associated with agonist
1) Confidence 0.24 Published 2008 Journal BMC Immunol Section Title Doc Link PMC2584092 Disease Relevance 0.15 Pain Relevance 0.33
It can be hypothesized that Bv8 affects the induction of specific IL-10-producing T cells, but future detailed studies are needed to characterise the T lymphocytes targeted by Bv8 to reduce IL-10 production.
Bv8 Negative_regulation (reduce) of Gene_expression (production) of IL-10 in T lymphocytes
2) Confidence 0.21 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2584092 Disease Relevance 0.09 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox