INT253102

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Stk11) mitochondrion (Stk11) nucleus (Stk11)
cell cycle (Stk11) protein complex (Stk11) kinase activity (Stk11)
Anatomy Link Frequency
skeletal muscle 1
Stk11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 17 78.08 Quite High
tolerance 6 58.52 Quite High
agonist 10 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 99.12 Very High Very High Very High
Insulin Resistance 40 61.96 Quite High
Impaired Glucose Tolerance 3 58.52 Quite High
Obesity 20 32.88 Quite Low
Diabetes Mellitus 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Hyperinsulinism 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, deficiency of LKB1 in skeletal muscle was reported to prevent AMPK activation and glucose uptake during contraction (37), although muscle contraction activates AMPK by a mechanism independent of direct activation of LKB1 (38).
Negative_regulation (deficiency) of LKB1 in skeletal muscle
1) Confidence 0.31 Published 2008 Journal Diabetes Section Body Doc Link PMC2584126 Disease Relevance 0.22 Pain Relevance 0.07

General Comments

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