INT253176

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Context Info
Confidence 0.23
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.61
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Parp1) nuclear envelope (Parp1) nucleolus (Parp1)
nucleus (Parp1) protein complex (Parp1) transcription factor binding (Parp1)
Anatomy Link Frequency
embryos 2
Parp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 2 94.60 High High
agonist 14 50.00 Quite Low
Inflammatory response 4 25.20 Quite Low
Inflammation 41 14.00 Low Low
cytokine 5 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
carrageenan induced 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gestational Diabetes 9 99.82 Very High Very High Very High
Diabetes Mellitus 50 85.60 High High
Pleurisy 16 81.52 Quite High
Congenital Anomalies 8 62.84 Quite High
Apoptosis 30 50.00 Quite Low
Fetal Diseases 2 44.84 Quite Low
Pressure And Volume Under Development 5 33.80 Quite Low
INFLAMMATION 42 24.84 Low Low
Lung Injury 3 21.52 Low Low
Urological Neuroanatomy 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of T0901317 on carrageenan-induced nitrotyrosine formation, lipid peroxidation and PARP activation
Regulation (Effects) of Gene_expression (activation) of PARP
1) Confidence 0.23 Published 2010 Journal Respir Res Section Body Doc Link PMC2836283 Disease Relevance 0.15 Pain Relevance 0
Maternal diabetes did not alter embryonic p53 (as noted previously [43]) and PARP expression in the present study, despite a putative PARP activity increase due to the presence of DNA damage in the MD embryos (29).
Neg (not) Regulation (alter) of Gene_expression (expression) of PARP in embryos associated with gestational diabetes
2) Confidence 0.11 Published 2008 Journal Diabetes Section Body Doc Link PMC2584142 Disease Relevance 0.46 Pain Relevance 0.05

General Comments

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