INT253187

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Shh) Golgi apparatus (Shh) endoplasmic reticulum (Shh)
embryo development (Shh) cell-cell signaling (Shh) signal transducer activity (Shh)
Anatomy Link Frequency
lower jaw 1
embryos 1
Shh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 2 62.32 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 50 97.12 Very High Very High Very High
Gestational Diabetes 9 96.28 Very High Very High Very High
Apoptosis 10 50.00 Quite Low
Congenital Anomalies 8 30.56 Quite Low
Fetal Diseases 2 12.56 Low Low
Stress 5 5.00 Very Low Very Low Very Low
Exencephaly /

Neural Tube Defects

2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Despite the absence of a significant difference in Shh mRNA levels between the MDn and MDm embryos, the decreased Shh expression in the MD offspring is of particular interest in relation to the findings of embryonic craniofacial (56) and aortic (57) anomalies resulting from direct inhibition of Shh, as well as the findings of an early role for Shh in securing the neural crest cell survival in the early development of the lower jaw (58).
Negative_regulation (absence) of in embryos Transcription (levels) of Shh in lower jaw
1) Confidence 0.41 Published 2008 Journal Diabetes Section Body Doc Link PMC2584142 Disease Relevance 0.55 Pain Relevance 0.03

General Comments

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