INT253190

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.77
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.06
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

anatomical structure formation involved in morphogenesis (Shh) Golgi apparatus (Shh) endoplasmic reticulum (Shh)
embryo development (Shh) cell-cell signaling (Shh) signal transducer activity (Shh)
Anatomy Link Frequency
MSCs 3
embryo 1
Shh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fibrosis 4 95.04 Very High Very High Very High
cytokine 13 92.88 High High
Inflammation 6 45.68 Quite Low
ischemia 4 36.84 Quite Low
Neuronal nitric oxide synthase 4 35.68 Quite Low
anesthesia 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Kinase C 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 96.88 Very High Very High Very High
Fibrosis 4 95.04 Very High Very High Very High
Apoptosis 14 86.96 High High
Diabetes Mellitus 50 85.40 High High
Gestational Diabetes 9 66.80 Quite High
Congenital Anomalies 8 56.64 Quite High
Parkinson's Disease 1 50.16 Quite High
INFLAMMATION 10 45.68 Quite Low
Injury 8 43.32 Quite Low
Cancer 6 38.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The anticipated objective of our multipronged strategy was to achieve intracrine, autocrine, and paracrine effects of Shh protein which was secreted from MSCs overexpressing Shh (ShhMSCs) and regenerated the damaged tissue, induced revascularization and concomitantly prevented remodeling of the heart by preserving the existing myocardium.
Localization (secreted) of Shh protein in MSCs
1) Confidence 0.77 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797399 Disease Relevance 0.09 Pain Relevance 0
The anticipated objective of our multipronged strategy was to achieve intracrine, autocrine, and paracrine effects of Shh protein which was secreted from MSCs overexpressing Shh (ShhMSCs) and regenerated the damaged tissue, induced revascularization and concomitantly prevented remodeling of the heart by preserving the existing myocardium.
Localization (secreted) of Shh in MSCs
2) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797399 Disease Relevance 0.09 Pain Relevance 0
The anticipated objective of our multipronged strategy was to achieve intracrine, autocrine, and paracrine effects of Shh protein which was secreted from MSCs overexpressing Shh (ShhMSCs) and regenerated the damaged tissue, induced revascularization and concomitantly prevented remodeling of the heart by preserving the existing myocardium.
Localization (secreted) of ShhMSCs in MSCs
3) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797399 Disease Relevance 0.09 Pain Relevance 0
In particular, the SODs, Gpx-1, and Shh genes decreased and VEGF increased in the Nm embryo, thus indicating a coupling to oxidative stress and neural crest cell development.
Localization (decreased) of Shh in embryo associated with stress
4) Confidence 0.71 Published 2008 Journal Diabetes Section Body Doc Link PMC2584142 Disease Relevance 0.70 Pain Relevance 0
Enhanced angiogenesis may be attributed to the multiple effects of localized Shh transgene expression.
Localization (localized) of Shh transgene
5) Confidence 0.67 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797399 Disease Relevance 0.10 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox