INT25333

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Context Info
Confidence 0.44
First Reported 1984
Last Reported 2003
Negated 0
Speculated 0
Reported most in Title
Documents 5
Total Number 5
Disease Relevance 1.73
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Tbxas1) endoplasmic reticulum (Tbxas1) molecular_function (Tbxas1)
cellular_component (Tbxas1)
Anatomy Link Frequency
paw 2
lymph 2
heart 2
Tbxas1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 4 99.84 Very High Very High Very High
cva 7 95.24 Very High Very High Very High
aspirin 1 94.44 High High
dexamethasone 1 90.56 High High
qutenza 1 77.76 Quite High
Inflammation 1 70.24 Quite High
acular 4 68.48 Quite High
anesthesia 1 68.32 Quite High
COX2 1 25.00 Low Low
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hepatotoxicity 2 99.36 Very High Very High Very High
Burns 7 99.32 Very High Very High Very High
Pressure And Volume Under Development 4 98.76 Very High Very High Very High
Injury 2 95.92 Very High Very High Very High
Pulmonary Embolism 7 95.64 Very High Very High Very High
Death 1 95.48 Very High Very High Very High
Cough 1 77.36 Quite High
Increased Venous Pressure Under Development 2 42.88 Quite Low
Pressure Volume 2 Under Development 1 25.00 Low Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our objective was to test the effect of inhibition of thromboxane synthase versus inhibition of cyclooxygenase (COX)-1/2 on pulmonary gas exchange and heart function during simulated pulmonary embolism (PE) in the rat.
Regulation (effect) of Negative_regulation (inhibition) of thromboxane synthase in heart associated with pulmonary embolism and cva
1) Confidence 0.44 Published 2003 Journal Am. J. Physiol. Lung Cell Mol. Physiol. Section Abstract Doc Link 12639842 Disease Relevance 0.42 Pain Relevance 0.33
Effect of antirheumatics and inhibitors of cyclooxygenase, lipoxygenases and thromboxane synthetase on cobra venom factor rat paw edema.
Regulation (Effect) of Negative_regulation (inhibitors) of thromboxane synthetase in paw associated with pressure and volume under development
2) Confidence 0.31 Published 1984 Journal Biomed. Biochim. Acta Section Title Doc Link 6440543 Disease Relevance 0.20 Pain Relevance 0.18
We studied the effect of inhibiting thromboxane synthetase, using dazmegrel, on postburn hemodynamic stability and edema formation, the latter monitored by burn tissue lymph flow.
Regulation (effect) of Negative_regulation (inhibiting) of thromboxane synthetase in lymph associated with pressure and volume under development and burns
3) Confidence 0.19 Published 1989 Journal Surgery Section Abstract Doc Link 2705099 Disease Relevance 0.59 Pain Relevance 0.07
[Effects of a thromboxane-synthetase inhibitor in patients with chronic persistent coughing and no airwayhyperresponsiveness].
Regulation ([Effects) of Negative_regulation (inhibitor) of thromboxane-synthetase
4) Confidence 0.13 Published 1997 Journal Nihon Kyobu Shikkan Gakkai Zasshi Section Title Doc Link 9396248 Disease Relevance 0.08 Pain Relevance 0.11
Effects of inhibitors of phospholipase A2, cyclooxygenase and thromboxane synthetase on paracetamol hepatotoxicity in the rat.
Regulation (Effects) of Negative_regulation (inhibitors) of thromboxane synthetase associated with paracetamol and hepatotoxicity
5) Confidence 0.07 Published 1989 Journal Eicosanoids Section Title Doc Link 2516744 Disease Relevance 0.45 Pain Relevance 0.25

General Comments

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