INT253340

Context Info Confidence 0.08 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0.52

signal transduction (GRIK1) transport (GRIK1) plasma membrane (GRIK1)

Anatomy Link Frequency neuronal 1 neurons 1 GRIK1 (Homo sapiens)

Pain Link Frequency Relevance Heat Electroencephalography 144 96.28 gABA 14 94.16 cerebral cortex 8 51.44 Pyramidal cell 6 18.60 Neurotransmitter 16 8.32 Hippocampus 14 5.00 isoflurane 8 5.00 Central nervous system 6 5.00 ketamine 6 5.00 hyperexcitability 4 5.00

Disease Link Frequency Relevance Heat Disease 2 16.32 Epilepsy 14 5.00 Cognitive Disorder 12 5.00 Unconsciousness 10 5.00 Coma 4 5.00 Anxiety Disorder 4 5.00 Depression 4 5.00 Amnesia 2 5.00 Convulsion 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Locally (i.e. within a macrocolumn), excitatory and inhibitory neuronal populations interact with each other and themselves.

excitatory Binding (interact) of in neuronal

1) Confidence 0.08 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.24

It assumes that all the various types of cortical neurons can be divided into synaptically interacting excitatory or inhibitory subpopulations.

excitatory Binding (interacting) of in neurons

2) Confidence 0.06 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.28

General Comments

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