INT253367

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6, Lep) extracellular region (Il6, Lep) aging (Il6)
intracellular (Lep) lipid metabolic process (Lep)
Anatomy Link Frequency
hypothalamus 4
Il6 (Rattus norvegicus)
Lep (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 10 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 78 98.72 Very High Very High Very High
Appetite Loss 28 62.16 Quite High
Body Weight 8 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next investigated the effect of IL-6 on leptin responsiveness in the hypothalamus of diet-induced obesity (DIO) rats after acute exercise.
IL-6 Spec (investigated) Regulation (effect) of Gene_expression (responsiveness) of leptin in hypothalamus associated with obesity
1) Confidence 0.31 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.89 Pain Relevance 0
The role of IL-6 on leptin responsiveness in the hypothalamus of diet-induced obesity (DIO) rats
IL-6 Regulation (role) of Gene_expression (responsiveness) of leptin in hypothalamus associated with obesity
2) Confidence 0.31 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.77 Pain Relevance 0

General Comments

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