INT253374

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.16
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Lep) extracellular region (Lep) nucleus (Eif4ebp1)
intracellular (Lep) protein complex (Eif4ebp1) cytoplasm (Eif4ebp1)
Anatomy Link Frequency
hypothalamus 2
Lep (Rattus norvegicus)
Eif4ebp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 10 53.20 Quite High
anesthesia 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 28 85.44 High High
Obesity 78 5.00 Very Low Very Low Very Low
Body Weight 8 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparing leptin treated groups (control vs. exercise), in exercised animals, leptin increased both p70S6K and 4EBP1 threonine phosphorylation of 30% and 40% respectively (Figures 5d and e).
leptin Positive_regulation (increased) of Phosphorylation (phosphorylation) of 4EBP1
1) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.09 Pain Relevance 0
Leptin induced p70S6K and 4EBP1 threonine phosphorylation in the hypothalamus of control and exercised rats.
Leptin Positive_regulation (induced) of Phosphorylation (phosphorylation) of 4EBP1 in hypothalamus
2) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.07 Pain Relevance 0.03

General Comments

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