INT253387

Context Info Confidence 0.28 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0.05

nucleoplasm (Prkaa2) nucleus (Prkaa2) protein binding, bridging (Prkaa2) protein complex (Prkaa2) response to stress (Prkaa2) cytoplasm (Prkaa2)

Anatomy Link Frequency hypothalamus 2 Prkaa2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat agonist 1 100.00 Intracerebroventricular 5 5.00 anesthesia 2 5.00 cytokine 1 5.00

Disease Link Frequency Relevance Heat Appetite Loss 14 75.88 Obesity 39 5.00 Body Weight 4 5.00 Aging 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Exercise partially reverses the effects of AMPK agonists and fasting on food intake through modulation of the AMPK-mTOR signaling pathway in the hypothalamus

Negative_regulation (reverses) of Regulation (modulation) of AMPK in hypothalamus associated with agonist

1) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.08 Pain Relevance 0.05

General Comments

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