INT253394

Context Info Confidence 0.28 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.33 Pain Relevance 0

nucleoplasm (Prkaa2) nucleus (Prkaa2) protein binding, bridging (Prkaa2) protein complex (Prkaa2) response to stress (Prkaa2) cytoplasm (Prkaa2)

Prkaa2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Intracerebroventricular 5 13.28 anesthesia 2 5.00 cytokine 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Appetite Loss 14 77.76 Obesity 39 68.56 Body Weight 4 5.00 Aging 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Both AMPK and ACC phosphorylation levels, reduced by exercise, were reversed by anti–IL-6 antibody (Figure 6c and d).

Negative_regulation (reversed) of Negative_regulation (reduced) of AMPK

1) Confidence 0.28 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2585815 Disease Relevance 0.33 Pain Relevance 0

General Comments

This test has worked.