INT253424

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Context Info
Confidence 0.74
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SFTPD) extracellular region (SFTPD) lysosome (SFTPD)
Anatomy Link Frequency
joint 1
lung 1
SFTPD (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 91.16 High High
rheumatoid arthritis 55 89.28 High High
Angina 1 40.52 Quite Low
Inflammatory response 2 40.48 Quite Low
methotrexate 9 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
visual analogue scale 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Disease 4 99.56 Very High Very High Very High
Pulmonary Alveolar Proteinosis 34 98.92 Very High Very High Very High
INFLAMMATION 13 91.16 High High
Rheumatoid Arthritis 55 89.28 High High
Arthritis 5 74.64 Quite High
Disease 27 53.56 Quite High
Respiratory Sounds 1 50.04 Quite High
Heart Rate Under Development 1 49.00 Quite Low
Apoptosis 2 46.00 Quite Low
Pneumonia 1 40.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This further supports that diffusion is the major source of SP-D in the joint cavity although local degradation of the molecule cannot be excluded.
Protein_catabolism (degradation) of SP-D in joint
1) Confidence 0.74 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888186 Disease Relevance 0.67 Pain Relevance 0.31
Because SP is in serum in PAP and levels reflect lung disease severity (25), serum SP-D was measured and found to be increased in the patient compared with her parents and controls (Fig. 1 D).
Protein_catabolism (measured) of SP-D in lung associated with pulmonary disease and pulmonary alveolar proteinosis
2) Confidence 0.06 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585845 Disease Relevance 0.45 Pain Relevance 0

General Comments

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