INT253487

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fpr3) mitosis (Ncapg2) plasma membrane (Fpr3)
nucleus (Ncapg2) cell cycle (Ncapg2) cell division (Ncapg2)
Ncapg2 (Mus musculus)
Fpr3 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 16 78.16 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
cOX1 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 96 100.00 Very High Very High Very High
Necrosis 54 97.04 Very High Very High Very High
Infection 61 52.84 Quite High
Apoptosis 32 16.68 Low Low
Death 20 5.00 Very Low Very Low Very Low
INFLAMMATION 14 5.00 Very Low Very Low Very Low
Sprains And Strains 10 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results not only provide additional proof that LXA4 suppresses PGE2 production but demonstrate that the induction of LXA4 by Mtb is a potential mechanism that prevents PGE2 production and leads to cell necrosis.


Mtb Positive_regulation (induction) of LXA4 associated with mycobacterial infection and necrosis
1) Confidence 0.21 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2585850 Disease Relevance 0.73 Pain Relevance 0.08

General Comments

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