INT253570

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Context Info
Confidence 0.16
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Csnk2a2, Sp3) intracellular (Sp3) DNA binding (Sp3)
cell cycle (Csnk2a2) kinase activity (Csnk2a2)
Csnk2a2 (Mus musculus)
Sp3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 69.44 Quite High
cytokine 26 68.80 Quite High
Inflammatory response 6 5.00 Very Low Very Low Very Low
IPN 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 22 70.80 Quite High
INFLAMMATION 14 69.44 Quite High
Obesity 4 56.20 Quite High
Disease 6 29.44 Quite Low
Disorder Of Lipid Metabolism 4 27.48 Quite Low
Cytomegalovirus Infection 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Renal Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The CK2- and PI3K-mediated regulation of Sp1/Sp3 binding could represent one such mechanism.


CK2 Binding (binding) of Sp1/Sp3
1) Confidence 0.16 Published 2008 Journal Cell Signal Section Body Doc Link PMC2586094 Disease Relevance 0.06 Pain Relevance 0
CK2 interacted with both Sp1 and Sp3 and this association was increased by IFN-?.
CK2 Binding (interacted) of Sp3
2) Confidence 0.16 Published 2008 Journal Cell Signal Section Abstract Doc Link PMC2586094 Disease Relevance 0.14 Pain Relevance 0.07

General Comments

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