INT25362

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Context Info
Confidence 0.26
First Reported 1988
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.52
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFKBIA) plasma membrane (NFKBIA) nucleus (NFKBIA)
enzyme binding (NFKBIA) transcription factor binding (NFKBIA) cytoplasm (NFKBIA)
Anatomy Link Frequency
T-cell 1
NFKBIA (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuritis 2 100.00 Very High Very High Very High
Pain 3 87.56 High High
Inflammation 21 83.48 Quite High
Arthritis 106 80.60 Quite High
peptic ulcer disease 1 79.72 Quite High
cytokine 17 60.32 Quite High
dexamethasone 7 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spontaneous Remission 2 100.00 Very High Very High Very High
Optic Neuritis 2 100.00 Very High Very High Very High
Immunoblastic Lymphadenopathy 2 99.98 Very High Very High Very High
Alagille Syndrome 2 96.20 Very High Very High Very High
Recurrence 1 92.36 High High
Pain 3 87.56 High High
Weight Loss 1 87.12 High High
Duodenal Ulcer 1 87.08 High High
Anaemia 1 86.60 High High
Infection 3 86.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These 2 M-components precipitated with anti-human kappa light chain antiserum but failed to react with lambda-light chain specific and H-chains specific anti-sera.
kappa light chain antiserum Binding (precipitated) of
1) Confidence 0.26 Published 1989 Journal Arch Inst Pasteur Alger Section Abstract Doc Link 2518743 Disease Relevance 0.34 Pain Relevance 0.09
The heterodimer_association of NFKBIA and NFKB1 is included in a large cycle in Module 2.
NFKBIA Binding (heterodimer_association) of
2) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2855702 Disease Relevance 0.47 Pain Relevance 0.11
A case of angioimmunoblastic lymphadenopathy associated with a long spontaneous remission, retrobulbar neuritis, a clonal rearrangement of the T-cell receptor gamma chain gene and an unusual marrow infiltration.
chain gene Binding (associated) of in T-cell associated with optic neuritis, immunoblastic lymphadenopathy, neuritis and spontaneous remission
3) Confidence 0.05 Published 1988 Journal Eur. J. Haematol. Section Title Doc Link 2846343 Disease Relevance 0.68 Pain Relevance 0.19
NF-kappaB DNA-binding and cytosolic IkappaB-alpha were measured using electrophoretic mobility shift assay and Western blotting.
IkappaB-alpha Binding (binding) of
4) Confidence 0.01 Published 2005 Journal J. Cell. Biochem. Section Abstract Doc Link 16088959 Disease Relevance 1.03 Pain Relevance 0.16

General Comments

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