INT253760

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.53
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Hmgb1, Apex1) nucleus (Hmgb1, Apex1) cytoplasm (Hmgb1, Apex1)
nucleolus (Hmgb1, Apex1) nucleoplasm (Apex1) mitochondrion (Apex1)
Anatomy Link Frequency
monocytes 10
Hmgb1 (Mus musculus)
Apex1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 135 96.44 Very High Very High Very High
chemokine 25 86.16 High High
Inflammatory stimuli 10 59.96 Quite High
Inflammation 180 8.48 Low Low
cytokine 115 7.44 Low Low
Inflammatory mediators 75 5.00 Very Low Very Low Very Low
vagus nerve 30 5.00 Very Low Very Low Very Low
cINOD 25 5.00 Very Low Very Low Very Low
Neuropeptide 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 25 100.00 Very High Very High Very High
INFLAMMATION 415 96.08 Very High Very High Very High
Dengue 5 92.08 High High
Infection 90 91.44 High High
Anaemia 5 91.36 High High
Injury 70 90.40 High High
Necrosis 20 52.80 Quite High
Apoptosis 55 37.60 Quite Low
Adhesions 5 5.36 Low Low
Sepsis 495 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Accumulating evidence indicates that HMGB1 can stimulating migration of neurites (Ref.
             61), smooth muscle cells (Ref. 62), tumour cells (Ref. 63), mesoangioblast stem cells (Refs 64, 65), monocytes (Ref.
             66), dendritic cells (Refs 67, 68)
           and neutrophils (Ref. 69) (Fig. 2). 
HMGB1 Positive_regulation (stimulating) of Gene_expression (migration) of Ref in monocytes associated with cancer
1) Confidence 0.10 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.69 Pain Relevance 0.11
Accumulating evidence indicates that HMGB1 can stimulating migration of neurites (Ref.
             61), smooth muscle cells (Ref. 62), tumour cells (Ref. 63), mesoangioblast stem cells (Refs 64, 65), monocytes (Ref.
             66), dendritic cells (Refs 67, 68)
           and neutrophils (Ref. 69) (Fig. 2). 
HMGB1 Positive_regulation (stimulating) of Gene_expression (migration) of Ref in monocytes associated with cancer
2) Confidence 0.10 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.71 Pain Relevance 0.12
Accumulating evidence indicates that HMGB1 can stimulating migration of neurites (Ref.
             61), smooth muscle cells (Ref. 62), tumour cells (Ref. 63), mesoangioblast stem cells (Refs 64, 65), monocytes (Ref.
             66), dendritic cells (Refs 67, 68)
           and neutrophils (Ref. 69) (Fig. 2). 
HMGB1 Positive_regulation (stimulating) of Gene_expression (migration) of Ref in monocytes associated with cancer
3) Confidence 0.10 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.70 Pain Relevance 0.12
Accumulating evidence indicates that HMGB1 can stimulating migration of neurites (Ref.
             61), smooth muscle cells (Ref. 62), tumour cells (Ref. 63), mesoangioblast stem cells (Refs 64, 65), monocytes (Ref.
             66), dendritic cells (Refs 67, 68)
           and neutrophils (Ref. 69) (Fig. 2). 
HMGB1 Positive_regulation (stimulating) of Gene_expression (migration) of Ref in monocytes associated with cancer
4) Confidence 0.09 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.70 Pain Relevance 0.11
Accumulating evidence indicates that HMGB1 can stimulating migration of neurites (Ref.
             61), smooth muscle cells (Ref. 62), tumour cells (Ref. 63), mesoangioblast stem cells (Refs 64, 65), monocytes (Ref.
             66), dendritic cells (Refs 67, 68)
           and neutrophils (Ref. 69) (Fig. 2). 
HMGB1 Positive_regulation (stimulating) of Gene_expression (migration) of Ref in monocytes associated with cancer
5) Confidence 0.09 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.73 Pain Relevance 0.12

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox