INT253766

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Apex1, Tlr4) cytoplasm (Apex1, Tlr4) nucleoplasm (Apex1)
mitochondrion (Apex1) lyase activity (Apex1) aging (Apex1)
Apex1 (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 88.16 High High
chemokine 5 82.24 Quite High
Inflammatory response 27 82.16 Quite High
Inflammation 36 77.76 Quite High
Inflammatory mediators 15 57.60 Quite High
vagus nerve 6 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 83 81.80 Quite High
Infection 18 66.48 Quite High
Injury 14 65.44 Quite High
Apoptosis 11 56.76 Quite High
Disease 14 36.56 Quite Low
Sepsis 99 35.20 Quite Low
Death 2 34.92 Quite Low
Lifespan 1 28.64 Quite Low
Cancer 5 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, TLR2 is
         essential for the recognition of lipoproteins, peptidoglycan and lipoteichoic acids of
         most Gram-positive bacteria (Ref. 10); TLR4
         recognises endotoxin of Gram-negative bacteria (Ref. 11); and TLR9 recognises microbial unmethylated CpG-DNA (Ref. 8).
Ref Binding (recognises) of TLR4
1) Confidence 0.03 Published 2008 Journal Expert Reviews in Molecular Medicine Section Body Doc Link PMC2586610 Disease Relevance 0.53 Pain Relevance 0.32

General Comments

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