INT253811

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck) DNA binding (Cck)
Cck (Mus musculus)
Pain Link Frequency Relevance Heat
Cholecystokinin 97 100.00 Very High Very High Very High
medulla 27 97.92 Very High Very High Very High
Somatostatin 46 91.24 High High
abdominal pain 1 71.04 Quite High
antagonist 14 57.16 Quite High
cocaine 3 50.00 Quite Low
Pain 1 47.76 Quite Low
headache 2 28.56 Quite Low
pruritus 1 27.76 Quite Low
Eae 13 25.12 Quite Low
Disease Link Frequency Relevance Heat
Gallstones 8 98.52 Very High Very High Very High
Vomiting 1 71.52 Quite High
Abdominal Pain 1 71.04 Quite High
Diarrhoea 1 70.40 Quite High
Acromegaly 36 50.00 Quite Low
Pain 1 47.76 Quite Low
Heart Rate Under Development 1 30.88 Quite Low
Asthenia 1 29.36 Quite Low
Headache 1 28.56 Quite Low
Pruritus 1 27.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The post hoc test showed a significant effect (P < 0.01) of parallel administration of CCK-8 and CART peptide on the Fos activation of cells in NTS in comparison with all other groups of animals (Fig. 3a, d).
Negative_regulation (effect) of Localization (administration) of CCK-8 associated with medulla and cholecystokinin
1) Confidence 0.41 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2587474 Disease Relevance 0 Pain Relevance 0.58
The formation of gallstones involves the inhibition of gallbladder emptying and intestinal motility, inhibition of the secretion of pro-kinetic peptides, including cholecystokinin, and increased intestinal and biliary production of deoxycholic acid, all of which promote the nucleation of cholesterol crystals and their aggregation into stones (Dowling et al 1992).
Negative_regulation (inhibition) of Localization (secretion) of cholecystokinin associated with gallstones and cholecystokinin
2) Confidence 0.10 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721386 Disease Relevance 0.76 Pain Relevance 0.28

General Comments

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