INT253864

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 13
Total Number 14
Disease Relevance 6.84
Pain Relevance 6.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PNP) small molecule metabolic process (PNP) cytoskeleton (PNP)
intracellular (PNP) cytoplasm (PNP)
Anatomy Link Frequency
collar 2
PNP (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 730 100.00 Very High Very High Very High
backache 610 100.00 Very High Very High Very High
shoulder pain 10 47.04 Quite Low
depression 10 29.48 Quite Low
anesthesia 3 9.08 Low Low
Central nervous system 10 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Demyelination 3 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 610 100.00 Very High Very High Very High
Neck Pain 590 100.00 Very High Very High Very High
Repression 4 97.84 Very High Very High Very High
Pain 140 97.48 Very High Very High Very High
Body Weight 10 74.60 Quite High
Shoulder Pain 10 47.04 Quite Low
Depression 10 29.48 Quite Low
Anxiety Disorder 10 29.04 Quite Low
Stress 16 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, the working group is asked for their opinions on: 1) the content and process of the working group meeting as a whole; 2) the ergonomist's competences; and 3) their expectations towards the implementation and the effectiveness of the ergonomic measures on the prevention of LBP and NP.
Negative_regulation (prevention) of NP associated with pain and backache
1) Confidence 0.26 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.56 Pain Relevance 0.56
To the workers allocated to the control departments are asked to watch three short (45 seconds) web-based educative movies about the prevention of LBP and NP at the campaign website of 'Lighten the load, a European Campaign on Musculoskeletal Disorders' developed by the European Agency for Safety and Health at Work.
Negative_regulation (prevention) of NP associated with pain and backache
2) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.53 Pain Relevance 0.53
Workers allocated to the intervention departments watch the same movies about the prevention of LBP and NP as the control group.
Negative_regulation (prevention) of NP associated with pain and backache
3) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.79 Pain Relevance 0.79
Prevention of LBP and NP is beneficial for workers, employers, and society.
Negative_regulation (Prevention) of NP associated with pain and backache
4) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC2588446 Disease Relevance 0.75 Pain Relevance 0.75
The company perspective compares the intervention costs paid by the company with 1) the effect on the prevalence of LBP and NP; 2) the effect on sick leave (in days) [67]; and 3) work productivity.
Negative_regulation (prevalence) of NP associated with pain and backache
5) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.48 Pain Relevance 0.41
Another approach to prevent LBP and NP may be participatory ergonomics (PE).
Negative_regulation (prevent) of NP associated with pain and backache
6) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 1.25 Pain Relevance 1.25
If proven (cost-)effective, the companies will benefit from a bottom-up method to prevent LBP and NP among their workers.
Negative_regulation (prevent) of NP associated with pain and backache
7) Confidence 0.19 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.20 Pain Relevance 0.20
As shown in Figure 4, the cell-associated green fluorescent NP was reduced by chlorpromazine and filipin, with filipin exerting a more evident inhibition.
Negative_regulation (reduced) of NP
8) Confidence 0.11 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
After removal of the NP suspension, cells were washed thrice with cold PBS followed by digestion in cell lysis buffer for 30 min.
Negative_regulation (removal) of NP
9) Confidence 0.11 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
This procedure reduces the HSA NP size from the reported >200 nm to about 120 nm, as shown in Table 1.
Negative_regulation (reduces) of NP
10) Confidence 0.11 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2768759 Disease Relevance 0 Pain Relevance 0
Although PE was (cost-)effective as a RTW intervention, no RCT has been conducted to evaluate the (cost-)effectiveness of PE to prevent LBP and NP among a large and heterogeneous population of workers (blue and white collar).
Negative_regulation (prevent) of NP in collar associated with pain and backache
11) Confidence 0.09 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.74 Pain Relevance 0.74
The movies show certain risk factors at work (i.e. lifting too heavy loads, frequent twisting of the lower back, holding the neck in a fore ward bent position for a prolonged time) for LBP and NP as well as (ergonomic) strategies to avoid these risk factors and, thereby, prevent LBP and NP.
Negative_regulation (prevent) of NP in neck associated with pain and backache
12) Confidence 0.09 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2588446 Disease Relevance 0.81 Pain Relevance 0.81
The Stay@Work study investigates the (cost-)effectiveness of Participatory Ergonomics (PE) to prevent LBP and NP among workers.


Spec (investigates) Negative_regulation (prevent) of NP associated with pain and backache
13) Confidence 0.09 Published 2008 Journal BMC Musculoskelet Disord Section Abstract Doc Link PMC2588446 Disease Relevance 0.64 Pain Relevance 0.64
Similarly, the EB-NP stage transition showed modest downregulation, with a maximum ?
Negative_regulation (downregulation) of EB-NP
14) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864763 Disease Relevance 0.10 Pain Relevance 0

General Comments

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