INT253894

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 1.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1b) cytoplasm (Htr1b) signal transducer activity (Htr1b)
Anatomy Link Frequency
neuronal 2
Htr1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuronal excitability 2 99.92 Very High Very High Very High
Sumatriptan 43 99.30 Very High Very High Very High
Opioid 10 94.80 High High
Periaqueductal grey 55 93.28 High High
agonist 14 92.64 High High
analgesia 3 92.48 High High
Cannabinoid 5 91.16 High High
GABAergic 27 88.24 High High
Neurotransmitter 5 70.20 Quite High
Rostral ventromedial medulla 3 63.52 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 55 93.28 High High
Pain 9 55.28 Quite High
Nociception 2 35.56 Quite Low
INFLAMMATION 1 20.00 Low Low
Neuropathic Pain 1 15.28 Low Low
Headache 10 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low
Photophobia 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is also possible that 5-HT and sumatriptan modulate neuronal excitability by direct 5-HT1B, D and F receptor mediated postsynaptic actions, as previously demonstrated for ?
Regulation (direct) of Localization (receptor) of 5-HT1B in neuronal associated with sumatriptan and neuronal excitability
1) Confidence 0.44 Published 2008 Journal Mol Pain Section Body Doc Link PMC2588575 Disease Relevance 0.61 Pain Relevance 1.82

General Comments

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