INT253895

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Htr1b, Htr1d) signal transducer activity (Htr1b, Htr1d) cytoplasm (Htr1b)
Htr1b (Rattus norvegicus)
Htr1d (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Sumatriptan 43 99.74 Very High Very High Very High
GABAergic 27 96.88 Very High Very High Very High
Neurotransmitter 5 95.28 Very High Very High Very High
Opioid 10 93.60 High High
Cannabinoid 5 92.96 High High
Periaqueductal grey 55 92.68 High High
agonist 14 90.08 High High
Rostral ventromedial medulla 3 88.60 High High
Analgesic 8 82.92 Quite High
Spinal cord 3 82.04 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 55 92.68 High High
Nociception 2 60.64 Quite High
Headache 10 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low
Photophobia 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present findings have demonstrated that sumatriptan, acting via 5-HT1B and 5-HT1D receptors, produces presynaptic disinhibition, similar to that previously observed for ?
5-HT1B Binding (receptors) of 5-HT1D associated with sumatriptan
1) Confidence 0.40 Published 2008 Journal Mol Pain Section Body Doc Link PMC2588575 Disease Relevance 0.52 Pain Relevance 1.74

General Comments

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