INT253973

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Context Info
Confidence 0.49
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) cytoplasmic membrane-bounded vesicle (Cxcr4) plasma membrane (Cxcr4)
signal transducer activity (Cxcr4)
Anatomy Link Frequency
bladder 2
Cxcr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 33 100.00 Very High Very High Very High
cytokine 6 97.22 Very High Very High Very High
chemokine 19 63.12 Quite High
Crohn's disease 1 7.20 Low Low
Arthritis 2 6.52 Low Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Stimulus evoked pain 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 34 100.00 Very High Very High Very High
Cystitis 17 100.00 Very High Very High Very High
Bladder Cancer 3 75.28 Quite High
Injury 6 58.56 Quite High
Body Weight 5 50.96 Quite High
Disease 3 7.20 Low Low
Arthritis 2 6.52 Low Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we examined: 1) location of cytokine receptor CXCR4 in the rat bladder; 2) baseline bladder levels of SDF-1 (cognate ligand for CXCR4) and changes in response to a chemically-induced (cyclophosphamide; CYP) model of bladder inflammation; 3) CXCR4 expression changes after CYP-induced cystitis and 4) association between CXCR4 and MIF in the bladder before and after CYP-induced cystitis.
Positive_regulation (induced) of CXCR4 Binding (association) of in bladder associated with inflammation, cystitis and cytokine
1) Confidence 0.49 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0.83 Pain Relevance 0.24

General Comments

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