INT253981

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.70
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl12) plasma membrane (Cxcl12)
Anatomy Link Frequency
bladder 4
Cxcl12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 38 76.00 Quite High
cytokine 14 67.44 Quite High
Inflammation 68 39.52 Quite Low
imagery 45 5.00 Very Low Very Low Very Low
dorsal root ganglion 8 5.00 Very Low Very Low Very Low
Stimulus evoked pain 4 5.00 Very Low Very Low Very Low
halothane 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
positron emission tomography 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 150 98.92 Very High Very High Very High
Injury 12 81.52 Quite High
Stress Incontinence 2 74.20 Quite High
Cystitis 34 50.00 Quite Low
Bladder Cancer 6 49.40 Quite Low
INFLAMMATION 70 39.52 Quite Low
Necrosis 1 38.68 Quite Low
Glioma 29 5.00 Very Low Very Low Very Low
Body Weight 10 5.00 Very Low Very Low Very Low
Ganglion Cysts 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, down-regulation of SDF-1 mRNA expression in the bladder (and other pelvic viscera) was reported afer vaginal distension [29].
Negative_regulation (down-regulation) of Gene_expression (expression) of SDF-1 mRNA in bladder
1) Confidence 0.39 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0.22 Pain Relevance 0.13
Cyclosphosphamide increased bladder SDF-1 levels
Negative_regulation (bladder) of Gene_expression (levels) of SDF-1 in bladder
2) Confidence 0.38 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0 Pain Relevance 0
Higher expression levels of VEGF, SDF-1 and HIF-1?
Negative_regulation (levels) of Gene_expression (expression) of SDF-1
3) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2806917 Disease Relevance 1.49 Pain Relevance 0

General Comments

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