INT253984

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Context Info
Confidence 0.80
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.65
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) cytoplasmic membrane-bounded vesicle (Cxcr4) plasma membrane (Cxcr4)
signal transducer activity (Cxcr4)
Cxcr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 46 98.64 Very High Very High Very High
chemokine 71 94.80 High High
Neuropathic pain 12 91.28 High High
Inflammation 35 77.60 Quite High
painful pain 1 72.60 Quite High
Peripheral nerve injury 3 43.28 Quite Low
Dorsal horn 2 37.08 Quite Low
Spinal cord 2 36.60 Quite Low
nociceptor 5 35.16 Quite Low
c fibre 2 34.68 Quite Low
Disease Link Frequency Relevance Heat
Injury 39 99.82 Very High Very High Very High
Ganglion Cysts 46 98.64 Very High Very High Very High
Neuropathic Pain 17 91.28 High High
Hyperplasia 2 78.68 Quite High
INFLAMMATION 38 77.60 Quite High
Nociception 7 72.60 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 21 50.00 Quite Low
Cystitis 17 50.00 Quite Low
Bladder Cancer 3 50.00 Quite Low
Nervous System Injury 8 42.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CYP treatment although producing CXCR4 mRNA upregulation (a novel finding) did not result in increased CXCR4 protein levels, and scoring of CXCR4 immunostaining actually showed a decrease in staining intensity following CYP treatment.
Phosphorylation (scoring) of CXCR4
1) Confidence 0.80 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0.16 Pain Relevance 0.07
Injury induced alteration of CXCR4 mRNA and protein expression in lumbar DRG
Phosphorylation (alteration) of CXCR4 mRNA associated with dorsal root ganglion and injury
2) Confidence 0.68 Published 2009 Journal Mol Pain Section Body Doc Link PMC2734548 Disease Relevance 0.49 Pain Relevance 0.36

General Comments

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