INT253999

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Context Info
Confidence 0.41
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.26
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl12, Mif) isomerase activity (Mif) aging (Mif)
cytoplasm (Mif) cell proliferation (Mif) extracellular region (Mif)
Anatomy Link Frequency
bladder 1
Cxcl12 (Rattus norvegicus)
Mif (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 99 95.84 Very High Very High Very High
chemokine 57 95.16 Very High Very High Very High
Stimulus evoked pain 6 91.12 High High
dorsal root ganglion 12 80.96 Quite High
substance P 3 68.72 Quite High
cytokine 18 53.52 Quite High
Crohn's disease 3 39.24 Quite Low
Arthritis 6 38.56 Quite Low
Lasting pain 3 33.12 Quite Low
Inflammatory stimuli 3 24.72 Low Low
Disease Link Frequency Relevance Heat
Colon Cancer 3 97.68 Very High Very High Very High
Injury 18 97.36 Very High Very High Very High
Inflammatory Bowel Disease 3 96.40 Very High Very High Very High
INFLAMMATION 102 95.00 High High
Bladder Cancer 9 92.32 High High
Pain 9 91.12 High High
Hypersensitivity 6 90.72 High High
Ganglion Cysts 12 80.00 Quite High
Cystitis 51 72.24 Quite High
Neuropathic Pain 3 56.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MIF, however, competed with the recognized ligand for CXCR4 (SDF-1/CXCL12) for binding to CXCR4 [18].
CXCL12 Binding (ligand) of MIF
1) Confidence 0.41 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0.50 Pain Relevance 0.28
The results from the present study indicate that MIF, by associating with CXCR4 receptors in the bladder (presumably urothelial in origin), may be competing with SDF-1 at CXCR4 receptors to participate in epithelial repair following injury.
SDF-1 Binding (competing) of MIF in bladder associated with injury
2) Confidence 0.36 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 1.26 Pain Relevance 0.65
MIF, however, competed with the recognized ligand for CXCR4 (SDF-1/CXCL12) for binding to CXCR4 [18].
SDF-1 Binding (ligand) of MIF
3) Confidence 0.31 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2588654 Disease Relevance 0.50 Pain Relevance 0.28

General Comments

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