INT25400

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Context Info
Confidence 0.11
First Reported 1989
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.02
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger1, Ptger2) plasma membrane (Ptger1, Ptger2) signal transducer activity (Ptger1, Ptger2)
Anatomy Link Frequency
PGE2 1
Ptger1 (Mus musculus)
Ptger2 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 94.00 High High
antagonist 1 78.64 Quite High
cINOD 8 63.20 Quite High
aspirin 1 39.28 Quite Low
Inflammation 16 32.28 Quite Low
endometriosis 2 28.44 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 1 98.16 Very High Very High Very High
Ovarian Cancer 42 93.12 High High
Familial Adenomatous Polyposis 1 92.88 High High
Apoptosis 1 87.52 High High
Targeted Disruption 1 82.96 Quite High
Cancer 60 79.60 Quite High
Vibrio Infection 1 56.40 Quite High
Malignant Neoplastic Disease 44 50.48 Quite High
Breast Cancer 2 43.68 Quite Low
INFLAMMATION 20 36.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PGE2 is ligand for at least four membrane-bound receptors, EP1–4.
EP1 Binding (ligand) of PGE2 in PGE2
1) Confidence 0.11 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1657027 Disease Relevance 0.97 Pain Relevance 0.10
Most interesting, however, was the finding that PGE2 and PGE1 could act synergistically with IL-2 for the induction of GM-CSF in some TH1 clones.
PGE1 Binding (act) of PGE2
2) Confidence 0.00 Published 1989 Journal J. Immunol. Section Abstract Doc Link 2521509 Disease Relevance 0.06 Pain Relevance 0.05

General Comments

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