INT25401

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Context Info
Confidence 0.43
First Reported 1985
Last Reported 1989
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mme) plasma membrane (Mme)
Mme (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 9 100.00 Very High Very High Very High
Analgesic 2 98.20 Very High Very High Very High
Opioid 1 88.60 High High
substance P 2 83.96 Quite High
Potency 2 82.92 Quite High
Central nervous system 1 65.80 Quite High
Disease Link Frequency Relevance Heat
Natriuresis 1 80.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A newly synthesized specific inhibitor of NEP was also active in animal experiments as an analgesic.
Negative_regulation (inhibitor) of Gene_expression (synthesized) of NEP associated with analgesic
1) Confidence 0.43 Published 1989 Journal FASEB J. Section Abstract Doc Link 2521610 Disease Relevance 0.08 Pain Relevance 0.57
Synthesis and biological evaluation of phosphonamidate peptide inhibitors of enkephalinase and angiotensin-converting enzyme.
Negative_regulation (inhibitors) of Gene_expression (Synthesis) of enkephalinase associated with enkephalin
2) Confidence 0.37 Published 1985 Journal J. Med. Chem. Section Title Doc Link 2993614 Disease Relevance 0 Pain Relevance 0.52

General Comments

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