INT254016

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.04
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (Kcna6)
Anatomy Link Frequency
proximal 2
Kcna6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
midbrain 2 86.08 High High
Dopamine 3 85.36 High High
imagery 11 78.16 Quite High
Action potential 7 71.84 Quite High
potassium channel 3 64.00 Quite High
unmyelinated 1 9.12 Low Low
Central nervous system 13 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Pyramidal cell 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Middle Cerebral Artery Infarction 1 99.56 Very High Very High Very High
Alzheimer's Dementia 4 98.20 Very High Very High Very High
Drug Induced Neurotoxicity 1 96.88 Very High Very High Very High
Hypoxia 7 94.96 High High
Neuroblastoma 1 93.84 High High
Disease 17 90.72 High High
Apoptosis 166 78.60 Quite High
Death 31 77.84 Quite High
Neurodegenerative Disease 14 42.40 Quite Low
Stress 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This targeting of Kv2.1 to a single proximal neurite was observed with little or no clustering on the cell body.
Regulation (targeting) of Gene_expression (This) of Kv2 in proximal
1) Confidence 0.31 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2592246 Disease Relevance 0 Pain Relevance 0.07
Up-regulation of Kv1.4, Kv2.1 and Kv4.2 expression both mRNA and protein levels is observed in amyloid peptide (25-35) -induced neurotoxicity [103].
Regulation (regulation) of Gene_expression (expression) of Kv2 associated with drug induced neurotoxicity and alzheimer's dementia
2) Confidence 0.18 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647147 Disease Relevance 1.04 Pain Relevance 0.15

General Comments

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