INT254051

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (RBP2) cytosol (RBP2) small molecule metabolic process (RBP2)
Golgi apparatus (RBP2) cytoplasm (RBP2)
RBP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 68 98.78 Very High Very High Very High
Disease 48 94.64 High High
Ovarian Cancer 122 93.20 High High
Carcinoma 52 70.20 Quite High
Residual Neoplasm 2 56.12 Quite High
Abdominal Pain 2 25.00 Low Low
Death 10 5.00 Very Low Very Low Very Low
Endometroid Carcinoma 4 5.00 Very Low Very Low Very Low
Lymphatic System Cancer 2 5.00 Very Low Very Low Very Low
Breast Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparing biomarker expression in the entire cohort for tumors diagnosed at different stages revealed that ten biomarkers (CRABP-II, ER, F-Spondin, K-Cadherin, Ki-67, Matriptase, Mesothelin, p21, p53, and WT1) had significantly different expression levels between stages, suggesting differences between “early” and “late” stage disease (Figure 2, Table S2).
Gene_expression (p21) of CRABP-II associated with cancer and disease
1) Confidence 0.65 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2592352 Disease Relevance 0.65 Pain Relevance 0
In this retrospective study we assessed the protein expression of 21 candidate tissue-based biomarkers (CA125, CRABP-II, EpCam, ER, F-Spondin, HE4, IGF2, K-Cadherin, Ki-67, KISS1, Matriptase, Mesothelin, MIF, MMP7, p21, p53, PAX8, PR, SLPI, TROP2, WT1) in a population-based cohort of 500 ovarian carcinomas that was collected over the period from 1984 to 2000.
Gene_expression (expression) of CRABP-II associated with ovarian cancer
2) Confidence 0.58 Published 2008 Journal PLoS Medicine Section Abstract Doc Link PMC2592352 Disease Relevance 0.53 Pain Relevance 0

General Comments

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