INT254119

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.34
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Bcl2a1a, Tlr4) signal transduction (Tlr4) plasma membrane (Tlr4)
intracellular (Tlr4)
Anatomy Link Frequency
endothelial cells 1
Bcl2a1a (Mus musculus)
Tlr4 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 30 97.48 Very High Very High Very High
Inflammation 60 95.04 Very High Very High Very High
Central nervous system 10 62.40 Quite High
adenocard 146 50.00 Quite Low
agonist 26 5.00 Very Low Very Low Very Low
ischemia 10 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 122 98.80 Very High Very High Very High
INFLAMMATION 36 95.04 Very High Very High Very High
Pneumonia 40 93.72 High High
Increased Venous Pressure Under Development 8 84.08 Quite High
Heart Rate Under Development 2 80.36 Quite High
Injury 24 58.52 Quite High
Pressure And Volume Under Development 10 54.24 Quite High
Lung Injury 12 48.64 Quite Low
Vibrio Infection 2 38.32 Quite Low
Disease 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of LPS to A1 leads to increased secretion of interleukin-6 and thromboxane A2, which can be significantly reduced by administration of a selective A1 antagonist [44].
A1 Binding (Binding) of LPS associated with antagonist
1) Confidence 0.01 Published 2008 Journal Crit Care Section Body Doc Link PMC2592730 Disease Relevance 0.62 Pain Relevance 0.25
Interestingly, LPS has been shown to be a ligand for A1 on human pulmonary endothelial cells.
A1 Binding (ligand) of LPS in endothelial cells
2) Confidence 0.01 Published 2008 Journal Crit Care Section Body Doc Link PMC2592730 Disease Relevance 0.73 Pain Relevance 0.24

General Comments

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