INT254197

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mif, Ptgs2) nucleus (Mif, Ptgs2) isomerase activity (Mif)
endoplasmic reticulum (Ptgs2) enzyme binding (Ptgs2) protein complex (Ptgs2)
Mif (Mus musculus)
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 1 100.00 Very High Very High Very High
Arthritis 15 98.04 Very High Very High Very High
Inflammation 36 91.44 High High
antagonist 4 87.44 High High
chemokine 3 85.52 High High
rheumatoid arthritis 65 76.00 Quite High
cytokine 26 69.28 Quite High
Inflammatory mediators 7 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 18 98.04 Very High Very High Very High
Apoptosis 2 97.88 Very High Very High Very High
INFLAMMATION 45 91.44 High High
Rheumatoid Arthritis 65 76.00 Quite High
Disease 24 60.88 Quite High
Death 4 51.36 Quite High
Necrosis 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MIF is also able to negatively regulate p53 [114] through cyclooxygenase 2 [115] and the PI3K/Akt pathway [116] to arrest cell-apoptosis.
MIF Regulation (regulate) of cyclooxygenase 2 associated with cox2 and apoptosis
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592774 Disease Relevance 1.08 Pain Relevance 0.55

General Comments

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