INT254199

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.75
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Socs3) extracellular space (Il10) extracellular region (Il10)
intracellular (Il10) cytoplasm (Socs3)
Il10 (Mus musculus)
Socs3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 63 98.96 Very High Very High Very High
agonist 2 98.68 Very High Very High Very High
chemokine 5 93.84 High High
Inflammation 49 74.00 Quite High
rheumatoid arthritis 66 71.28 Quite High
Arthritis 15 61.20 Quite High
adenocard 11 5.00 Very Low Very Low Very Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
substance P 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 60 74.00 Quite High
Autoimmune Disease 10 72.32 Quite High
Rheumatoid Arthritis 66 71.28 Quite High
Arthritis 18 65.24 Quite High
Disease Progression 2 63.44 Quite High
Multiple Sclerosis 4 50.72 Quite High
Uveitis 1 41.00 Quite Low
Disease 58 30.12 Quite Low
Infection 10 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, they also found that IL-10 up-regulated the expression of the socs-3 gene.
IL-10 Positive_regulation (regulated) of Gene_expression (expression) of socs-3
1) Confidence 0.06 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2654796 Disease Relevance 0.15 Pain Relevance 0.32
It should also be noted that IL-10 is able to strongly induce the expression of SOCS-3, a classic suppressor of cytokine signalling [121].
IL-10 Positive_regulation (induce) of Gene_expression (expression) of SOCS-3 associated with cytokine
2) Confidence 0.04 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592774 Disease Relevance 0.59 Pain Relevance 0.32

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox