INT2542

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.81
First Reported 1979
Last Reported 2010
Negated 15
Speculated 30
Reported most in Abstract
Documents 2008
Total Number 2040
Disease Relevance 518.30
Pain Relevance 1408.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca) aging (Calca) extracellular region (Calca)
nucleus (Calca) intracellular (Calca) cytoplasm (Calca)
Anatomy Link Frequency
nerve 144
neurons 110
sensory nerves 104
spinal cord 81
sensory neurons 55
Calca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 12098 100.00 Very High Very High Very High
qutenza 7755 100.00 Very High Very High Very High
Glutamate 3287 100.00 Very High Very High Very High
Pain 2622 100.00 Very High Very High Very High
Migraine 2587 100.00 Very High Very High Very High
Inflammation 2409 100.00 Very High Very High Very High
antagonist 2313 100.00 Very High Very High Very High
substance P 2162 100.00 Very High Very High Very High
Neurotransmitter 1952 100.00 Very High Very High Very High
Spinal cord 1602 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Ganglion Cysts 2704 100.00 Very High Very High Very High
Pain 2428 100.00 Very High Very High Very High
INFLAMMATION 2242 100.00 Very High Very High Very High
Nociception 1584 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 1115 100.00 Very High Very High Very High
Hypoxia 445 100.00 Very High Very High Very High
Migraine Disorders 105 100.00 Very High Very High Very High
Natriuresis 44 100.00 Very High Very High Very High
Cv Unclassified Under Development 319 99.96 Very High Very High Very High
Headache 2960 99.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Time-course of capsaicin-evoked release of calcitonin gene-related peptide from rat spinal cord in vitro.
Localization (release) of calcitonin gene-related peptide in spinal cord associated with qutenza, spinal cord and calcitonin gene-related peptide
1) Confidence 0.81 Published 1992 Journal Regul. Pept. Section Title Doc Link 1374925 Disease Relevance 0 Pain Relevance 1.25
Release of CGRP evoked by capsaicin concentrations in the range of 0.1-0.3 microM in either dosage protocol was reduced in the presence of Ruthenium Red (RR, 2.5 microM).
Localization (Release) of CGRP associated with qutenza and calcitonin gene-related peptide
2) Confidence 0.81 Published 1992 Journal Regul. Pept. Section Abstract Doc Link 1374925 Disease Relevance 0 Pain Relevance 1.43
The capsaicin-evoked release of calcitonin gene-related peptide (CGRP) from rat superfused dorsal spinal cord slices was investigated during sustained capsaicin exposure thought to represent equilibrium conditions.
Spec (investigated) Localization (release) of CGRP in spinal cord associated with qutenza, spinal cord and calcitonin gene-related peptide
3) Confidence 0.81 Published 1992 Journal Regul. Pept. Section Abstract Doc Link 1374925 Disease Relevance 0 Pain Relevance 0.81
When cumulative dose regimens for capsaicin were employed, release of CGRP could be stimulated only up to a dose of 1-1.5 microM capsaicin; further increase in capsaicin concentration was ineffective.
Localization (release) of CGRP associated with qutenza and calcitonin gene-related peptide
4) Confidence 0.81 Published 1992 Journal Regul. Pept. Section Abstract Doc Link 1374925 Disease Relevance 0 Pain Relevance 1.37
The capsaicin-evoked release of calcitonin gene-related peptide (CGRP) from rat superfused dorsal spinal cord slices was investigated during sustained capsaicin exposure thought to represent equilibrium conditions.
Spec (investigated) Localization (release) of calcitonin gene-related peptide in spinal cord associated with qutenza, spinal cord and calcitonin gene-related peptide
5) Confidence 0.81 Published 1992 Journal Regul. Pept. Section Abstract Doc Link 1374925 Disease Relevance 0 Pain Relevance 0.81
Changes in the neurogenic release of calcitonin gene-related peptide (CGRP) by perivascular nerve stimulation (PNS) were investigated in perfused mesenteric vascular beds isolated from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY).
Localization (release) of CGRP in nerve associated with hypertension and calcitonin gene-related peptide
6) Confidence 0.81 Published 1992 Journal Clin Exp Hypertens A Section Abstract Doc Link 1424225 Disease Relevance 0.17 Pain Relevance 0.35
In young SHR and WKY (8-week-old), there was no significant difference in the release of CGRP-LI induced by PNS, whereas the release in the 15-week-old SHR was significantly less than in the 15-week-old WKY and in 8-week-old SHR.
Localization (release) of CGRP associated with calcitonin gene-related peptide
7) Confidence 0.81 Published 1992 Journal Clin Exp Hypertens A Section Abstract Doc Link 1424225 Disease Relevance 0.15 Pain Relevance 0.47
Age-related decrease of neurogenic release of calcitonin gene-related peptide from perivascular nerves in spontaneously hypertensive rats.
Localization (release) of calcitonin gene-related peptide in nerves associated with hypertension and calcitonin gene-related peptide
8) Confidence 0.81 Published 1992 Journal Clin Exp Hypertens A Section Title Doc Link 1424225 Disease Relevance 0.19 Pain Relevance 0.45
Changes in the neurogenic release of calcitonin gene-related peptide (CGRP) by perivascular nerve stimulation (PNS) were investigated in perfused mesenteric vascular beds isolated from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY).
Localization (release) of calcitonin gene-related peptide in nerve associated with hypertension and calcitonin gene-related peptide
9) Confidence 0.81 Published 1992 Journal Clin Exp Hypertens A Section Abstract Doc Link 1424225 Disease Relevance 0.17 Pain Relevance 0.35
Immersion of the hind paw of rats in water at 47 degrees C for 30 min led to a marked increase of immunoreactive CGRP (iCGRP) release as well as immunoreactive substance P release, but no detectable increase of immunoreactive neurokinin A release.
Localization (release) of CGRP in paw associated with substance p and calcitonin gene-related peptide
10) Confidence 0.81 Published 1991 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 1654475 Disease Relevance 0 Pain Relevance 0.32
The release of tachykinins and calcitonin gene-related peptide (CGRP) into subcutaneous perfusates was investigated.
Spec (investigated) Localization (release) of calcitonin gene-related peptide associated with calcitonin gene-related peptide
11) Confidence 0.81 Published 1991 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 1654475 Disease Relevance 0 Pain Relevance 0.30
The release of tachykinins and calcitonin gene-related peptide (CGRP) into subcutaneous perfusates was investigated.
Spec (investigated) Localization (release) of CGRP associated with calcitonin gene-related peptide
12) Confidence 0.81 Published 1991 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 1654475 Disease Relevance 0 Pain Relevance 0.30
It has been suggested that capsaicin-induced gastric mucosal protection results from the local release of vasodilator peptides such as calcitonin gene-related peptide (CGRP) from afferent nerve endings within the stomach, since CGRP is able to reduce gastric lesion formation.
Localization (release) of calcitonin gene-related peptide in stomach associated with qutenza and calcitonin gene-related peptide
13) Confidence 0.81 Published 1990 Journal Neurosci. Lett. Section Abstract Doc Link 2304629 Disease Relevance 0 Pain Relevance 0.52
It has been suggested that capsaicin-induced gastric mucosal protection results from the local release of vasodilator peptides such as calcitonin gene-related peptide (CGRP) from afferent nerve endings within the stomach, since CGRP is able to reduce gastric lesion formation.
Localization (release) of CGRP in stomach associated with qutenza and calcitonin gene-related peptide
14) Confidence 0.81 Published 1990 Journal Neurosci. Lett. Section Abstract Doc Link 2304629 Disease Relevance 0 Pain Relevance 0.52
Transient prevention of ethanol-induced gastric lesion by capsaicin due to release of endogenous calcitonin gene-related peptide in rats.
Localization (release) of calcitonin gene-related peptide associated with qutenza and calcitonin gene-related peptide
15) Confidence 0.81 Published 2001 Journal Jpn. J. Pharmacol. Section Title Doc Link 11488437 Disease Relevance 0 Pain Relevance 1.09
Effects of 17 beta-estradiol and the Japanese herbal medicine Keishi-bukuryo-gan on the release and synthesis of calcitonin gene-related peptide in ovariectomized rats.
Localization (release) of calcitonin gene-related peptide associated with calcitonin gene-related peptide
16) Confidence 0.81 Published 2003 Journal J. Pharmacol. Sci. Section Title Doc Link 14501156 Disease Relevance 0 Pain Relevance 0.49
The purpose of this study is to clarify the effects of 17beta-estradiol and the Japanese herbal medicine Keishi-bukuryo-gan on the release and synthesis of calcitonin gene-related peptide (CGRP) in ovariectomized (OVX) rats.
Localization (release) of calcitonin gene-related peptide associated with calcitonin gene-related peptide
17) Confidence 0.81 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14501156 Disease Relevance 0 Pain Relevance 0.45
These results suggest not only that estrogen deficiency attenuates CGRP release but also that 17beta-estradiol or Keishi-bukuryo-gan normalizes the attenuated release process.
Localization (release) of CGRP associated with calcitonin gene-related peptide
18) Confidence 0.81 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14501156 Disease Relevance 0 Pain Relevance 0.47
The purpose of this study is to clarify the effects of 17beta-estradiol and the Japanese herbal medicine Keishi-bukuryo-gan on the release and synthesis of calcitonin gene-related peptide (CGRP) in ovariectomized (OVX) rats.
Localization (release) of CGRP associated with calcitonin gene-related peptide
19) Confidence 0.81 Published 2003 Journal J. Pharmacol. Sci. Section Abstract Doc Link 14501156 Disease Relevance 0 Pain Relevance 0.45
On the other hand, the capsaicin-induced CGRP release was not blocked by tetrodotoxin treatment.
Localization (release) of CGRP associated with tetrodotoxin, qutenza and calcitonin gene-related peptide
20) Confidence 0.81 Published 1996 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 8957683 Disease Relevance 0 Pain Relevance 1.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox