INT254208

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Chuk) extracellular space (Il10) extracellular region (Il10)
nucleus (Chuk) intracellular (Il10) kinase activity (Chuk)
Il10 (Mus musculus)
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 65 83.76 Quite High
Inflammation 36 83.12 Quite High
Arthritis 15 73.68 Quite High
cytokine 26 72.96 Quite High
chemokine 3 18.24 Low Low
COX2 1 10.64 Low Low
Inflammatory mediators 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 65 83.76 Quite High
INFLAMMATION 45 83.12 Quite High
Arthritis 18 77.72 Quite High
Disease Progression 2 75.92 Quite High
Autoimmune Disease 2 47.36 Quite Low
Disease 24 42.60 Quite Low
Apoptosis 2 13.12 Low Low
Necrosis 6 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-10 has been reported to reduce the activity of the IKK signalosome and induce the translocation of NF-?
IL-10 Negative_regulation (reduce) of Regulation (activity) of IKK
1) Confidence 0.05 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592774 Disease Relevance 0.59 Pain Relevance 0.29

General Comments

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