INT254277

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Hand1, Tnfsf11) cytoplasm (Hand1, Tnfsf11) nucleoplasm (Hand1)
intracellular (Tnfsf11) enzyme binding (Hand1) DNA binding (Hand1)
Hand1 (Mus musculus)
Tnfsf11 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 100.00 Very High Very High Very High
Arthritis 18 39.84 Quite Low
Inflammation 18 16.72 Low Low
rheumatoid arthritis 25 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 4 82.16 Quite High
Arthritis 23 39.84 Quite Low
Pressure And Volume Under Development 5 36.08 Quite Low
Disease 9 24.64 Low Low
Lyme Disease 1 13.40 Low Low
Rheumatoid Arthritis 25 5.00 Very Low Very Low Very Low
INFLAMMATION 17 5.00 Very Low Very Low Very Low
Hypercalcemia 6 5.00 Very Low Very Low Very Low
Synovitis 5 5.00 Very Low Very Low Very Low
Nervous System Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased osteoclasto-genesis effect may well be due to a Th1 proinflammatory cytokine TNF, which is known to synergize with RANKL.
Th1 Binding (synergize) of RANKL associated with cytokine
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592787 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

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