INT254281

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il4, Acp5) extracellular region (Il4) lysosome (Acp5)
Anatomy Link Frequency
osteoclasts 2
Il4 (Mus musculus)
Acp5 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 75.92 Quite High
antagonist 3 64.96 Quite High
rheumatoid arthritis 25 58.36 Quite High
Inflammation 18 57.32 Quite High
Arthritis 18 51.04 Quite High
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 6 98.88 Very High Very High Very High
Osteoporosis 4 96.00 Very High Very High Very High
Rheumatoid Arthritis 25 58.36 Quite High
INFLAMMATION 17 57.32 Quite High
Arthritis 23 51.04 Quite High
Disease 9 43.04 Quite Low
Pressure And Volume Under Development 5 32.32 Quite Low
Synovitis 5 5.00 Very Low Very Low Very Low
Nervous System Inflammation 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mature osteoclasts express the IL-4 receptor, and exogenous IL-4 decreased tartrate-resistant acid phosphatase expression, actin ring formation, and bone resorption by osteoclasts [82].
IL-4 Negative_regulation (decreased) of Gene_expression (expression) of tartrate-resistant acid phosphatase in osteoclasts associated with hypercalcemia
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592787 Disease Relevance 0.41 Pain Relevance 0.22

General Comments

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