INT254283

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il10) extracellular region (Il10) nucleus (Nfatc1)
intracellular (Il10) DNA binding (Nfatc1) cytoplasm (Nfatc1)
Anatomy Link Frequency
osteoclasts 1
Il10 (Mus musculus)
Nfatc1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 23 89.72 High High
Inflammation 18 79.92 Quite High
rheumatoid arthritis 25 78.64 Quite High
Arthritis 18 27.04 Quite Low
antagonist 3 20.36 Low Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatic Diseases 1 95.04 Very High Very High Very High
INFLAMMATION 17 79.92 Quite High
Rheumatoid Arthritis 25 78.64 Quite High
Arthritis 23 27.04 Quite Low
Disease 9 5.00 Very Low Very Low Very Low
Hypercalcemia 6 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 5 5.00 Very Low Very Low Very Low
Synovitis 5 5.00 Very Low Very Low Very Low
Osteoporosis 4 5.00 Very Low Very Low Very Low
Nervous System Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IL-10, however, has a clear inhibitory effect on osteoclasts by downregulating NFATc1 [94].
IL-10 Negative_regulation (downregulating) of NFATc1 in osteoclasts
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592787 Disease Relevance 0.31 Pain Relevance 0.25

General Comments

This test has worked.

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