INT254298

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Context Info
Confidence 0.55
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 9.79
Pain Relevance 1.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (AES)
Anatomy Link Frequency
chest 2
AES (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 11 100.00 Very High Very High Very High
headache 17 96.52 Very High Very High Very High
Angina 9 95.28 Very High Very High Very High
pruritus 1 89.64 High High
Pain 10 88.64 High High
rheumatoid arthritis 35 82.16 Quite High
Central nervous system 1 42.84 Quite Low
Leflunomide 1 36.80 Quite Low
methotrexate 2 21.40 Low Low
cINOD 1 20.84 Low Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 9 100.00 Very High Very High Very High
Heart Rate Under Development 4 99.92 Very High Very High Very High
Leukopenia 9 99.88 Very High Very High Very High
Anaemia 6 99.30 Very High Very High Very High
Agammaglobulinemia 2 99.16 Very High Very High Very High
Fatigue 14 98.96 Very High Very High Very High
Dizziness 4 98.84 Very High Very High Very High
Increased Venous Pressure Under Development 8 98.76 Very High Very High Very High
Syncope 4 98.40 Very High Very High Very High
Dyspnea 4 98.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The other grade 1 or grade 2 AEs related to infusions included flushing (five patients), hypotension (three patients), headache (three patients), and chest pain, angioedema and bronchospasm (one case each).
Protein_catabolism (grade) of AEs in chest associated with pressure and volume under development, angina, pressure volume 2 under development, bronchospasm, headache and increased venous pressure under development
1) Confidence 0.55 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833973 Disease Relevance 1.95 Pain Relevance 0.30
Overall, 18 patients reported fatigue, four had anemia and two developed leukopenia, all grade 1 or 2 AEs.
Protein_catabolism (grade) of AEs associated with anaemia, leukopenia and fatigue
2) Confidence 0.55 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833973 Disease Relevance 1.84 Pain Relevance 0.28
The other grade 1 or grade 2 AEs related to infusions included flushing (five patients), hypotension (three patients), headache (three patients), and chest pain, angioedema and bronchospasm (one case each).
Protein_catabolism (grade) of AEs in chest associated with pressure and volume under development, angina, pressure volume 2 under development, bronchospasm, headache and increased venous pressure under development
3) Confidence 0.55 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC2833973 Disease Relevance 1.94 Pain Relevance 0.30
AEs were coded on the basis of the Medical Dictionary for Regulatory Activities terminology version 6.0 and were graded for severity according to the National Institutes of Health Division of Microbiology and Infectious Diseases Adult Toxicity Tables (Version May 2001).
Protein_catabolism (graded) of AEs associated with toxicity and communicable diseases
4) Confidence 0.21 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592791 Disease Relevance 0.46 Pain Relevance 0
Selected AEs associated with bevacizumab treatment included arterial thromboembolism (grade ?
Protein_catabolism (grade) of AEs associated with cva
5) Confidence 0.14 Published 2010 Journal OncoTargets and therapy Section Body Doc Link PMC2895775 Disease Relevance 1.87 Pain Relevance 0.34
AEs (solicited and unsolicited) were graded from 0 to 3 (grade 0: no impairment; grade 1 (mild): easily tolerated; grade 2 (moderate): interference with daily activity; grade 3 (severe): prevention of daily activities), except for erythema and induration, which were graded on the size of the lesion measured by the investigator 48 h after injection (grade 1 (mild): 1–19 mm; grade 2 (moderate): 20–49 mm; grade 3 (severe): ?
Neg (except) Protein_catabolism (graded) of AEs associated with erythema
6) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2749339 Disease Relevance 1.73 Pain Relevance 0.23

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