INT254302

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.03
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ICOS) plasma membrane (ICOS)
Anatomy Link Frequency
macrophages 1
granulocyte 1
monocytes 1
dendritic cells 1
ICOS (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 8 100.00 Very High Very High Very High
antagonist 20 23.92 Low Low
Angina 12 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
headache 8 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 8 100.00 Very High Very High Very High
Cancer 8 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 200 99.40 Very High Very High Very High
Disease 104 92.48 High High
Autoimmune Disease 4 67.44 Quite High
Targeted Disruption 4 41.52 Quite Low
Hypergammaglobulinemia 4 33.68 Quite Low
Renal Disease 16 29.44 Quite Low
Proteinuria 4 19.84 Low Low
Neutropenia 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
B-lymphocyte stimulator (BLyS) is a member of the tumor necrosis factor (TNF) ligand superfamily of cytokines that is expressed and secreted by monocytes, macrophages, dendritic cells, and granulocyte colony-stimulating factor activated neutrophils [5,6].
Gene_expression (expressed) of stimulator in dendritic cells associated with necrosis, cancer and cytokine
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592791 Disease Relevance 1.01 Pain Relevance 0.05
B-lymphocyte stimulator (BLyS) is a member of the tumor necrosis factor (TNF) ligand superfamily of cytokines that is expressed and secreted by monocytes, macrophages, dendritic cells, and granulocyte colony-stimulating factor activated neutrophils [5,6].
Gene_expression (expressed) of stimulator in monocytes associated with necrosis, cancer and cytokine
2) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592791 Disease Relevance 1.01 Pain Relevance 0.05
B-lymphocyte stimulator (BLyS) is a member of the tumor necrosis factor (TNF) ligand superfamily of cytokines that is expressed and secreted by monocytes, macrophages, dendritic cells, and granulocyte colony-stimulating factor activated neutrophils [5,6].
Gene_expression (expressed) of stimulator in granulocyte associated with necrosis, cancer and cytokine
3) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592791 Disease Relevance 1.01 Pain Relevance 0.05
B-lymphocyte stimulator (BLyS) is a member of the tumor necrosis factor (TNF) ligand superfamily of cytokines that is expressed and secreted by monocytes, macrophages, dendritic cells, and granulocyte colony-stimulating factor activated neutrophils [5,6].
Gene_expression (expressed) of stimulator in macrophages associated with necrosis, cancer and cytokine
4) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592791 Disease Relevance 1.01 Pain Relevance 0.05

General Comments

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