INT254318

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 2.20 Pain Relevance 0

Anatomy Link Frequency renal tubule 2 Slc37a4 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 44 5.00 imagery 16 5.00 cytokine 12 5.00 Inflammatory response 12 5.00 cINOD 10 5.00 Arthritis 6 5.00 anakinra 6 5.00 corticosteroid 4 5.00 Central nervous system 2 5.00 Parenteral administration 2 5.00

Disease Link Frequency Relevance Heat Metabolic Syndrome 14 88.16 Hyperuricemia 74 85.40 Hypertension 18 81.68 Metabolic Disorder 2 46.00 Crystal Associated Disease 142 31.36 INFLAMMATION 58 5.00 Syndrome 8 5.00 Arthritis 6 5.00 Disease 6 5.00 Apoptosis 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The major transporter is urate transporter-1 (URAT-1), a urate-anion exchanger localized on the luminal side of the proximal renal tubule.

Localization (localized) of transporter in renal tubule

1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592794 Disease Relevance 1.11 Pain Relevance 0

The major transporter is urate transporter-1 (URAT-1), a urate-anion exchanger localized on the luminal side of the proximal renal tubule.

Localization (localized) of transporter in renal tubule

2) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592794 Disease Relevance 1.10 Pain Relevance 0

General Comments

This test has worked.