INT254349

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (EPAS1, HIF1A) signal transduction (EPAS1, HIF1A) nucleus (EPAS1, HIF1A)
transcription factor binding (EPAS1, HIF1A) cytoplasm (EPAS1, HIF1A) signal transducer activity (EPAS1, HIF1A)
EPAS1 (Homo sapiens)
HIF1A (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 34 85.52 High High
cytokine 7 78.68 Quite High
Arthritis 29 77.60 Quite High
chemokine 59 75.88 Quite High
antagonist 4 73.20 Quite High
metalloproteinase 5 48.84 Quite Low
Inflammation 50 15.52 Low Low
methotrexate 7 5.00 Very Low Very Low Very Low
corticosteroid 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 10 100.00 Very High Very High Very High
Synovitis 4 88.96 High High
Rheumatoid Arthritis 34 85.52 High High
Arthritis 30 77.60 Quite High
Apoptosis 1 64.40 Quite High
Rheumatic Diseases 16 50.00 Quite Low
INFLAMMATION 50 15.52 Low Low
Disease 19 11.92 Low Low
Crohn's Disease 2 5.12 Low Low
Increased Venous Pressure Under Development 37 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypoxia acts through the hypoxia-inducible factor heterodimer, HIF-1?
Positive_regulation (acts) of hypoxia-inducible factor Binding (heterodimer) of HIF-1 associated with hypoxia
1) Confidence 0.00 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592799 Disease Relevance 0.92 Pain Relevance 0.23

General Comments

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