INT254370

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.24
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (THBS2) cell adhesion (THBS2) structural molecule activity (THBS2)
Anatomy Link Frequency
macrophages 1
fibroblasts 1
THBS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 68 99.84 Very High Very High Very High
Arthritis 58 98.60 Very High Very High Very High
Inflammation 100 91.84 High High
chemokine 118 87.20 High High
corticosteroid 12 86.52 High High
cytokine 14 65.64 Quite High
antagonist 8 49.92 Quite Low
Taxol 2 26.64 Quite Low
methotrexate 14 5.00 Very Low Very Low Very Low
metalloproteinase 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 68 99.84 Very High Very High Very High
Arthritis 60 98.60 Very High Very High Very High
INFLAMMATION 100 91.84 High High
Disease 38 87.36 High High
Rheumatic Diseases 32 58.00 Quite High
Microscopic Polyangiitis 2 55.16 Quite High
Syndrome 2 53.96 Quite High
Wegener's Granulomatosis 2 53.00 Quite High
Systemic Lupus Erythematosus 32 51.92 Quite High
Kawasaki Syndrome 2 46.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thrombospondin-1 and -2 are angiostatic ECM components produced by RA synovial macrophages and fibroblasts [16,32].
Gene_expression (produced) of Thrombospondin-1 and -2 in fibroblasts associated with rheumatoid arthritis
1) Confidence 0.06 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592799 Disease Relevance 1.12 Pain Relevance 0.50
Thrombospondin-1 and -2 are angiostatic ECM components produced by RA synovial macrophages and fibroblasts [16,32].
Gene_expression (produced) of Thrombospondin-1 and -2 in macrophages associated with rheumatoid arthritis
2) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592799 Disease Relevance 1.12 Pain Relevance 0.50

General Comments

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