INT254386

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 3.39
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (MRC1) plasma membrane (MRC1)
Anatomy Link Frequency
dendritic cells 4
MRC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 16 88.52 High High
cINOD 4 62.20 Quite High
tolerance 16 5.00 Very Low Very Low Very Low
dexamethasone 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Lupus Erythematosus 336 99.56 Very High Very High Very High
Adhesions 32 98.28 Very High Very High Very High
Disease 56 98.16 Very High Very High Very High
Congenital Anomalies 20 86.48 High High
INFLAMMATION 4 61.96 Quite High
Infection 32 5.00 Very Low Very Low Very Low
Apoptosis 20 5.00 Very Low Very Low Very Low
Autoimmune Disease 16 5.00 Very Low Very Low Very Low
Necrosis 12 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Decreased expression of the mannose receptor was associated with high serum IFN?
Negative_regulation (Decreased) of Gene_expression (expression) of mannose receptor
1) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Abstract Doc Link PMC2592801 Disease Relevance 0.86 Pain Relevance 0
Lupus dendritic cells have diminished endocytic capacity, which correlates with decreased mannose receptor expression.
Negative_regulation (decreased) of Gene_expression (expression) of mannose receptor in dendritic cells associated with systemic lupus erythematosus
2) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Abstract Doc Link PMC2592801 Disease Relevance 0.64 Pain Relevance 0
Decreased mannose receptor expression and endocytic capacity correlates with lupus disease activity
Negative_regulation (Decreased) of Gene_expression (expression) of mannose receptor associated with disease and systemic lupus erythematosus
3) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592801 Disease Relevance 1.02 Pain Relevance 0.15
SLE dendritic cells have decreased surface mannose receptor expression, which correlates with FITC-dextran uptake
Negative_regulation (decreased) of Gene_expression (expression) of mannose receptor in dendritic cells associated with systemic lupus erythematosus
4) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592801 Disease Relevance 0.87 Pain Relevance 0

General Comments

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