INT254441

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Calm2) nucleoplasm (Calm2) cytoskeleton (Calm2)
cell cycle (Calm2) cellular_component (Calm2) biological_process (Calm2)
Anatomy Link Frequency
nucleus 1
Calm2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 23 41.28 Quite Low
tetrodotoxin 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Action potential 3 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 4 27.96 Quite Low
Ganglion Cysts 14 5.00 Very Low Very Low Very Low
Channelopathies 8 5.00 Very Low Very Low Very Low
Shock 4 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Migraine With Aura 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, a simple variant of this allosteric mechanism, with f > 1, could explain CaM-induced facilitation in CaV2.1 channels (Chaudhuri et al., 2007).
Localization (facilitation) of CaM
1) Confidence 0.13 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2828906 Disease Relevance 0 Pain Relevance 0
, which along with CaM (Deisseroth et al., 1998; Sakagami et al., 2005) translocates to the nucleus upon depolarization (Sakagami et al., 2005).
Localization (translocates) of CaM in nucleus
2) Confidence 0.09 Published 2008 Journal The Journal of Cell Biology Section Body Doc Link PMC2592819 Disease Relevance 0 Pain Relevance 0

General Comments

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