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Context Info
Confidence 0.43
First Reported 1989
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.22
Pain Relevance 1.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nppa) nucleus (Nppa) cytoplasm (Nppa)
Anatomy Link Frequency
plasma 2
Nppa (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 6 100.00 Very High Very High Very High
antinociception 2 99.92 Very High Very High Very High
potassium channel 8 99.68 Very High Very High Very High
narcan 2 99.12 Very High Very High Very High
Morphine 4 98.04 Very High Very High Very High
opioid receptor 2 91.28 High High
diclofenac 6 83.52 Quite High
Antinociceptive 4 75.00 Quite High
cINOD 1 54.24 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Natriuresis 3 75.00 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the effect of clonidine on plasma ANP was partially blocked by pretreatment with naloxone (5 micrograms/min).
Negative_regulation (blocked) of Regulation (effect) of ANP in plasma associated with narcan and clonidine
1) Confidence 0.43 Published 1989 Journal Proc. Soc. Exp. Biol. Med. Section Abstract Doc Link 2525782 Disease Relevance 0.15 Pain Relevance 1.04
ANP effect was inhibited by the potassium channel blockers, but not by L-NAME, suggesting that potassium channel opening is a consequence of an increased cGMP content.
Negative_regulation (inhibited) of Regulation (effect) of ANP associated with potassium channel
2) Confidence 0.39 Published 2003 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 13679232 Disease Relevance 0.07 Pain Relevance 0.93

General Comments

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